GLP-1 and cardioprotection: from bench to bedside

Heme oxygenase-1: from bench to bedside.

As aspects of basic science come to play an increasingly prominent role in clinical medicine, heme oxygenase-1 is one of several molecules emerging as a central player in diseases of the lung and intensive care unit. Although the apparent raison d'être of this enzyme is to dispose of heme, its activity results in cytoprotection against oxidative injury and cellular stresses. As the lung interfa...

Lenalidomide: from bench to bedside (part 1).

From bench to bedside

Because the microcirculation has emerged as an important reanimation target, appropriate methods to monitor the microcirculatory function are crucial. Several teams have now succeeded in crossing this bridge from bench to bedside, but the choice of the tissues of interest remains a debate. The potential accessible vascular beds that doctors could use in reanimation strategies and the relationsh...

From Bench to Bedside

Since the initial experiments nearly a decade ago, remarkable progress has been made in the field of vascular gene transfer, and trials with human subjects already are under way. The potential of vascular wall gene transfer as therapy for various vascular diseases is considerable.1,2 The purpose of this review is 2-fold: (1) to delineate the methods and principles underlying vascular gene trans...

Nutrition: From Bench to Bedside

The nutritional health in the world is one of the most pressing issues facing different countries today. International organizations like FAO and WHO suggest that there is an improvement of the nutritional situation in Asia and Latin America, though a deterioration in Sub-Saharan Africa does exist. As regards Europe and USA, we are living in the era of " overnutrition. " Unfortunately, the situ...